A Role of Ginseng and Its Constituents in the Treatment of Central Nervous System Disorders
Table 1
Effects of ginseng and its metabolites in neurodegenerative disorder. AD: Alzheimer’s disease, PD: Parkinson’s disease, HD: Huntington’s disease, ALS: amyotrophic lateral sclerosis, and A: -amyloid.
Neurodegenerative disorder
Active compound
Research type
Mechanism
Reference
AD
Rb1, Rg1, Rg5, Rd, Re, gintonin, and ginseng extract panaxynol
Animal model and cell culture
Decrease A production and aggregation, increase A clearance, decrease of tau hyperphosphorylation, and improve cholinergic function