Research Article
Efficacy of Compound Kushen Injection in Combination with Induction Chemotherapy for Treating Adult Patients Newly Diagnosed with Acute Leukemia
Table 5
Grade 3/4 drug toxicity and adverse events occurring during the induction period in the treatment and control groups.
| | Variable | AML (%) | ALL (%) | | Treatment group () | Control group () | Treatment group () | Control group () |
| | Hematologic toxicity | 6 (6.8) | 21 (24.1) | 3 (3.8) | 17 (21.8) | | Gastrointestinal reaction | 2 (2.3) | 10 (11.5) | 1 (1.3) | 8 (10.3) | | Pneumonia | 1 (1.1) | 9 (10.3) | 1 (1.3) | 6 (7.7) | | Cardiotoxicity | 0 (0) | 4 (4.6) | 1 (1.3) | 5 (6.4) | | Hepatotoxicity | 3 (3.4) | 11 (12.6) | 2 (2.5) | 9 (11.5) | | Neurological dysfunction | 1 (1.1) | 7 () | 1 (1.3) | 8 (10.3) | | Renal dysfunction | 3 (3.4) | 16 (18.4) | 1 (1.3) | 11 (14.1) | | Skin reactions | 1 (1.1) | 7 () | 0 (0) | 5 (6.4) |
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Notes: AML: acute myeloid leukemia, ALL: acute lymphocytic leukemia. Compared with the control group, .
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