The Difference between the Two Representative Kampo Formulas for Treating Dysmenorrhea: An Observational Study
Table 3
Baseline characteristics of the patients included in the comparison and model-development analysis.
The comparison and model development set
value
Other formulas
TSS group
KBG group
Number of patients
60
68
N/A
86
Age at consultation
Mean ± SD
33.3 ± 7.9
32.5 ± 8.7
0.595
33.0 ± 8.1
Median
33
33
0.742
33
Range
17–50
12–50
13–49
N/A
0 (0.0)
0 (0.0)
0 (0.0)
Age at menarche, years
Mean ± SD
12.2 ± 1.5
12.3 ± 1.6
0.753
12.7 ± 1.6
Median
12
12
0.932
12
Range
9–16
9–17
9–17
N/A
0 (0.0)
2 (2.9)
2 (2.3)
Menstrual cycle, days
Mean ± SD
29.0 ± 5.7
29.3 ± 3.6
0.772
28.9 ± 4.5
Median
28
28
0.771
28
Range
16–60
25–45
17–60
N/A
6 (10.0)
16 (23.5)
10 (11.6)
Bleeding period, days
Mean ± SD
5.8 ± 1.3
5.9 ± 1.9
0.841
5.5 ± 1.6
Median
6
6
0.747
5
Range
3–9
3–14
3–14
N/A
4 (6.7)
9 (13.2)
7 (8.1)
BMI, kg/m2
Mean ± SD
19.8 ± 2.3
21.6 ± 3.5
0.001
20.6 ± 2.9
Median
19.4
21.0
0.000
20.0
Range
15.9–26.7
17.0–39.8
15.6–30.1
<18.5 (slim)
21 (35.0)
6 (8.8)
0.000
26 (30.2)
≥25 (obese)
2 (3.3)
9 (13.2)
0.060
7 (8.1)
N/A
2 (3.3)
1 (1.5)
4 (4.7)
Use of OCs
No
54 (90.0)
63 (92.6)
0.754
77 (89.5)
Yes
6 (10.0)
5 (7.4)
9 (10.5)
Delivery
No
54 (90.0)
62 (91.2)
1
75 (87.2)
Yes
6 (10.0)
6 (8.8)
11 (12.8)
Abortion
No
53 (88.3)
61 (89.7)
1
74 (86.0)
Yes
7 (11.7)
7 (10.3)
12 (14.0)
Diagnosed organic disease
No
52 (86.7)
53 (77.9)
0.251
81 (94.2)
Endometriosis
6 (10.0)
8 (11.8)
0.785
4 (4.7)
Adenomyosis
2 (3.3)
8 (11.8)
0.103
2 (2.3)
Infertility (primary and secondary)
No
59 (98.3)
64 (94.1)
0.370
81 (94.2)
Yes
1 (1.7)
4 (5.9)
5 (5.8)
TSS, tokishakuyakusan; KBG, keishibukuryogan; N/A, not available; BMI, body mass index; OCs, oral contraceptives. Findings are expressed as mean ± SD, median, range, or number with percentage in parentheses. values were calculated using -test, Wilcoxon’s rank sum test, and Fisher’s exact test.
