Evidence-Based Complementary and Alternative Medicine / 2016 / Article / Fig 3

Research Article

Synergistic Effect of Ferulic Acid and Z-Ligustilide, Major Components of A. sinensis, on Regulating Cold-Sensing Protein TRPM8 and TPRA1 In Vitro

Figure 3

Isobolograms of combination of ferulic acid with Z-ligustilide in inhibiting response to agonists. The individual doses of ferulic acid and Z-ligustilide to achieve 90% (straight line) inhibition (Fa = 0.90), 75% (hyphenated line) inhibition (Fa = 0.75), and 70% (crosses) inhibition (Fa = 0.70) were plotted on the -axes and -axes. Combination index (CI) values calculated by Calcusyn software are represented by points above (indicating antagonism) or below the lines (indicating synergism).

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.