Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation

Figure 6

THL sensitizes MCF-7 cells to radiation. (a) Cells were pretreated with THL for 24 h and then irradiated with 4–24 Gy of ionizing radiation as indicated. Colony formation of the irradiated cells was assayed after 8 days of incubation. (b) Representative picture of colony formed by the cells described in (a). Data (mean ± SE in triplicate) are expressed as a percentage of the PBS control. , compared to the respective THL free group treated with the same dose of radiation.

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(b)