Research Article

Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation

Table 3

Cell cycle phase distribution (%) of 72-hour THL-treated BT-474 cells showing increasing SubG1 fraction and S-phase arrest.

TreatmentSubG1 (%)Cell cycle distribution
G1 (%) S (%) G2/M (%)

PBS0.872.212.815.0
THL 0.75 mg/mL3.867.516.715.8
THL 1.5 mg/mL13.565.817.716.6
THL 3 mg/mL27.355.827.716.5
THL 6 mg/mL50.150.736.912.4