| | Author and year | Patients (EG/CG) | The average age | Intervention of EG | Intervention of CG | Outcomes | Duration |
| |
Deng et al., 2012 [25] | 53 (26/27) | EG: 62.54 ± 15.56
CG: 64.04 ± 13.84 | Intensive care monitoring, conventional western therapy, Shenfu injection 50 mL + 5% 250 mL GLU, iv drip, QD | Intensive care monitoring, conventional western therapy | Mortality | 7 d |
| | He et al., 2013 [19] | 250 (128/122) | Not reported | Intensive care monitoring, conventional western therapy, Shenfu injection 100 mL + 100 mL NS, iv drip, BID | Intensive care monitoring, conventional western therapy, 200 mL NS, iv drip, BID | Mortality | 14 d |
| | Hu, 2012 [24] | 80 (42/38) | EG: 57.8 ± 12.3
CG: 57.8 ± 12.3 | Intensive care monitoring, conventional western therapy, Shenfu injection 20 mL + 20 mL NS intravenous infusion (once every 30 min for 3 times), Shenfu injection 100 mL + 500 mL NS, iv drip | Intensive care monitoring, conventional western therapy | Mortality | 3–7 d |
| | Hu et al., 2009 [20] | 62 (33/29) | EG: 64.3 ± 8.9
CG: 69.5 ± 7.8 | Intensive care monitoring, conventional western therapy, Shenfu injection 40 mL, intravenous infusion, Shenfu 100 mL + 250 mL NS, iv drip | Intensive care monitoring, conventional western therapy, epinephrine 1 mg (once every 3-4 min), total amount less than 0.2 mg/kg | Mortality; the complication rate | 6 h |
| | Su et al., 2011 [23] | 60 (31/29) | EG: 48.1 ± 13.2
CG: 48.1 ± 13.2 | Intensive care monitoring, conventional western therapy, Shenfu injection 50 mL + 5% 100–250 mL GLU, iv drip, QD | Intensive care monitoring, conventional western therapy | Mortality | 14 d |
| | Liu, 2013 [27] | 47 (24/23) | EG: 53.3 ± 8.2
CG: 52.8 ± 7.8 | Intensive care monitoring, conventional therapy, prevention of complications, support and symptomatic treatment, Shenfu injection 100 mL, iv drip, QD | Intensive care monitoring, conventional therapy, prevention of complications, support and symptomatic treatment | Mortality; the complication rate | 3–7 d |
| | Xu et al., 2008 [22] | 80 (40/40) | EG: 49.71 ± 18.82
CG: 49.71 ± 18.82 | Intensive care monitoring, conventional therapy, Shenfu injection 20 mL + 5% 20 mL GLU intravenous infusion (once every 30 min for 3 times), Shenfu injection 100 mL + 450 mL NS, iv drip | Intensive care monitoring, conventional therapy | Mortality; the complication rate | Not reported |
| | Zhang and Sun, 2012 [26] | 62 (33/29) | EG: 48.2 ± 13.1
CG: 48.2 ± 13.1 | Intensive care monitoring, conventional therapy, vasoactive drugs, therapeutic hypothermia, and so forth, Shenfu injection 50 mL + 5% 100–250 mL GLU, iv drip, QD | Intensive care monitoring, conventional therapy, vasoactive drugs, therapeutic hypothermia, and so forth | Mortality | 14 d |
| | Sun et al., 2009 [18] | 60 (30/30) | Not reported | Intensive care monitoring, conventional therapy, Erhuang powder (18–21 g) ig, TID | Intensive care monitoring, conventional therapy, famotidine 20 mg iv drip | Mortality;
the complication rate | 7 d |
| | Yi et al., 2012 [21] | 40 (19/21) | EG: 70.16 ± 8.19
CG: 71.67 ± 9.64 | Intensive care monitoring, routine applications of rescue measures and emergency medicine, Shengmai injection 60 mL iv | Intensive care monitoring, routine applications of rescue measures and emergency medicine | Mortality; the complication rate | Not reported |
| | Zhao et al., 2007 [28] | 42 (23/19) | EG: 63.0 ± 8.7
CG: 67.8 ± 7.1 | Intensive care monitoring, conventional western therapy, Shengmai injection 50 mL, intravenous infusion, Shenfu 50 mL + 250 mL NS, iv drip | Intensive care monitoring, conventional western therapy | Mortality; the complication rate | Not reported |
| | Liang et al., 2013 [31] | 63 (33/30) | EG: 58 ± 26
CG: 61 ± 24 | Intensive care monitoring, conventional therapy, ventilation, circulatory support, therapeutic hypothermia, anti-infection, supportive care, and so forth, Sini decoction, 50 mL, nasal feeding, BID | Intensive care monitoring, conventional therapy, ventilation, circulatory support, therapeutic hypothermia, Anti-infection, supportive care, and so forth | Mortality | 14 d |
| | Liang et al., 2014 [30] | 86 (43/43) | EG: 58 ± 27
CG: 58 ± 27 | Intensive care monitoring, conventional western therapy, treatment of the primary disease, Xuebijing injection 100 mL + 250 mL NS, iv drip, BID | Intensive care monitoring, conventional western therapy, treatment of the primary disease | Mortality | 14 d |
| | Wu et al., 2009 [29] | 41 (19/22) | EG: 60.4 ± 11.1
CG: 61.3 ± 12.7 | Intensive care monitoring, conventional western therapy, treatment of the primary disease, Xuebijing injection 50 mL, iv drip, BID | Intensive care monitoring, conventional western therapy, treatment of the primary disease | Mortality; the complication rate | 7 d |
| | Li and Liu, 2014 [32] | 40 (20/20) | EG: 59.9 ± 60
CG: 59.9 ± 60 | Intensive care monitoring, conventional western therapy, etiological treatment, Xuefuzhuyujiawei decoction, BID | Intensive care monitoring, conventional western therapy, etiological treatment | Mortality | 7 d |
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