The Therapeutic Effect of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease: A Meta-Analysis

Table 1

Characteristics of the 6 included studies.

Study	Sample size,	Intervention of experimental group	Intervention of control group	Dose of berberine	Duration	Outcomes
Bai et al. 2011 [16]	78	BBR	ISI	0.5 g, tid	3 months	1, 2, 3, 5, 6, 7, 8, 11
Cao et al. 2012 [17]	78	BBR + metformin	Metformin	0.5 g, tid	16 weeks	1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
Li 2015 [18]	96	BBR	Acarbose	0.3 g, tid	3 months	1, 2, 3, 4, 5, 6, 7, 8, 9, 10
Ning et al. 2013 [19]	44	BBR + metformin	Metformin	0.5 g, tid	16 weeks	1, 2, 8, 10
Xie et al. 2011 [20]	60	BBR	Xuezhikang	0.3 g, tid	12 weeks	1, 2, 3, 4, 5, 6
Yan et al. 2015 [21]	155	BBR	ISI or pioglitazone	0.5 g, tid	16 weeks	1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11

1: TC; 2: TG; 3: LDL; 4: HDL; 5: ALT; 6: AST; 7: GGT; 8: FBG; 9: 2hPG; 10: HbA1c; 11: HOMA-IR.