Neuroprotective Effect of Paeonol Mediates Anti-Inflammation via Suppressing Toll-Like Receptor 2 and Toll-Like Receptor 4 Signaling Pathways in Cerebral Ischemia-Reperfusion Injured Rats

Figure 4

Effect of paeonol on the number of TLR2-, TLR4-, and Iba1-immunoreactive cells within the cortical penumbra in cerebral ischemia-reperfusion injured rats. (a) The numbers of TLR2-, TLR4-, and Iba1-immunoreactive cells (arrows) were lower in the paeonol group than in the control group. (200x); (b) the numbers of TLR2-, TLR4-, and Iba1-immunoreactive cells were significantly lower in the paeonol group than in the control group (). Data are expressed as mean ± SD. , , and compared with the sham group; , , and compared with the control group. N: negative control; sham: sham group; control: control group; paeonol: paeonol group.

(a)

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