Evidence-Based Complementary and Alternative Medicine / 2016 / Article / Tab 1

Research Article

The Score Model Containing Chinese Medicine Syndrome Element of Blood Stasis Presented a Better Performance Compared to APRI and FIB-4 in Diagnosing Advanced Fibrosis in Patients with Chronic Hepatitis B

Table 1

Characteristics of 709 CHB patients with ALT < 2ULN.

VariablesAll patients0 < ALT ≤ 4040 < ALT ≤ 80 value

Demographic characteristics
 Age (years), median (IQR)39.0 (31.5–46.0)39.0 (32.0–45.0)38.0 (31.0–47.0)0.823
 Males, (%)486 (68.5%)273 (62.6%)213 (78%)<0.001
Laboratory data
 ALT (IU/L), median (IQR) 35.0 (22.0–47.0)25.0 (18.0–33.0)51.0 (45.0–64.0)<0.001
 AST (IU/L), median (IQR) 26.0 (21.0–36.0)22.6 (19.0–27.0)36.0 (30.0–43.0)<0.001
 ALB (g/L), median (IQR) 44.1 (42.0–46.4)43.9 (42.0–46.1)44.4 (41.95–46.85)0.280
 GGT (IU/L), median (IQR)24.0 (17.5–38.0)21.0 (15.0–33.0)31.0 (22.0–45.0)<0.001
 PLT (109/L), median (IQR) 186 (152.0–224.0)187 (151.0–223.0)185 (152.0–225.0)0.828
 HBeAg (+), (%)331 (46.7%)178 (40.8%)153 (56.0%)<0.001
 HBV DNA (log10 IU/mL), median (IQR)5.49 (3.62–7.21)4.72 (3.24–6.79)6.29 (4.98–7.59)<0.001
Liver histology
 Inflammation activity, (%)
  G0–2, (%)600 (84.6%)380 (63.3%)220 (36.7%)0.018
  G3-4, (%)109 (15.4%)56 (51.4%)53 (48.6%)
 Fibrosis (%)
  F0–2, (%)477 (67.3%)296 (62.1%)181 (37.9%)0.661
  F3-4, (%)232 (32.7%)140 (60.3%)92 (39.7%)

ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; GGT, g-glutamyl transpeptidase; PLT, platelet; HBeAg: hepatitis B e antigen; IQR, interquartile range.