Medicinal Plants from Mexico, Central America, and the Caribbean Used as Immunostimulants

Table 5

In vivo immunostimulatory effects of plant compounds.

Family	Scientific name	Compound	Group	Model of immunosuppression and duration of the experiment [range of dose tested]	Immunostimulatory effects (compared to immunosuppressed mice)	Reference
Asteraceae	Psacalium peltatum (Kunth) Cass.	Maturin acetate	Sesquiterpene	BALB/c mice treated with 100 mg/kg cyclophosphamide for 14 days [10–50 mg/kg i.p.]	Production of IFN-γ (1.4-fold) and IL-2 (1.8-fold)	[56]
Rubiaceae	Uncaria tomentosa (Willd.) DC.	Pteropodine	Alkaloid	Immunocompetent mice for 4 days [100–600 mg/kg i.p.]	Lymphocyte proliferation (1.6-fold) at 600 mg/kg	[59]