Cardiovascular Effects of the Essential Oil of Croton argyrophylloides in Normotensive Rats: Role of the Autonomic Nervous System

Figure 4

Effects of increasing concentrations (1–1000 μg/mL) of the essential oil of Croton argyrophylloides (EOCA) on the contraction induced by phenylephrine (PHE, 1 μM) in rat isolated thoracic aortic preparations with () or without functional endothelium () and those pretreated with L-NAME (100 μM, ) (a) or in preparations pretreated with atropine (1 μM, ) or indomethacin (10 μM, ) (b) or pretreated with glibenclamide (100 μM, ) or TEA (5 mM, ) (c). Vertical bars indicate SEM. by Dunnett’s test with respect to basal values.

(a)

(b)

(c)