Antiobesity Effects of Unripe<i> Rubus coreanus</i> Miquel and Its Constituents: An<i> In Vitro</i> and<i> In Vivo</i> Characterization of the Underlying Mechanism

<div>Fractionation procedures for uRC are summarized by a diagrammatic scheme. uRC (30 g) was suspended in water and divided successively with hexane, CHCl<sub>3</sub>, EtOAc, and BuOH. The dried BuOH fraction was eluted on a silica gel column (5 × 40 cm; Merck, 63–200 <i>μ</i>m particle size) with a solvent gradient of CHCl<sub>3</sub> : MeOH (5 : 1 to 0 : 1 ratios) to yield six fractions (Fr.1–Fr.6). Fr.6 was analyzed as six bioactive compounds (S1–S6) using LC-ESI-MS/MS.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1: Antiobesity Effects of Unripe<i> Rubus coreanus</i> Miquel and Its Constituents: An<i> In Vitro</i> and<i> In Vivo</i> Characterization of the Underlying Mechanism 

Figure 1 | Antiobesity Effects of Unripe Rubus coreanus Miquel and Its Constituents: An In Vitro and In Vivo Characterization of the Underlying Mechanism 