Research Article

Intravenous Mistletoe Treatment in Integrative Cancer Care: A Qualitative Study Exploring the Procedures, Concepts, and Observations of Expert Doctors

Box 2

Case illustrations of favorite course of disease under MT infusions, as reported by interviewed doctors.
(i) A patient with breast cancer, lymphangiosis carcinomatosa and shortness of breath declined
chemotherapy and received mistletoe infusions (Iscador) every 3 weeks. Each time, this substantially
improved her breathing for a period of 2 weeks. She lived five years after diagnosis of
lymphangiosis and 10 years since diagnosis of breast cancer. (General practitioner)
(ii) One patient with a huge inoperable colorectal carcinoma, metastases in the liver and lymph
nodes and an additional renal cell cancer was first treated with intratumoral and subcutaneous
applications. The tumor became harder and encapsulated. Due to gastrointestinal bleeding, the
tumor, which had a weight of 5-6 kg, was removed (R0). After recovery from postoperative septic
complications, the patient received MT subcutaneously and intravenously. His condition improved
and stabilized. The patient returned to work despite his liver and bone metastases and lived for at
least 3 more years until he died of a sudden cardiac arrest. (Internist)
(iii) A patient over 70 years old with a partly resected metastatic sigmoid colon cancer (T4) refused
chemotherapy. She received infusions (Helixor, rhythmic dosages 100–500 mg) and lived well for 6 more
years. She later also agreed to a temporary oral capecitabine treatment. The ultrasound showed an
encapsulation of the tumor. After 6 years, the tumor induced heavy bleeding in the sigma and the
patient died. (General practitioner)
(iv) One patient with a large pseudomyxoma peritonei, encircling large parts of the colon, had been
treated with multiple operations, hyperthermia, chemotherapy and anthroposophic medicine. The
tumor led to a rectovaginal fistula. The patient was then treated with fever-inducing mistletoe infusions
(Iscador M spezial, 5 mg). A CT scan showed a slight improvement, and the fistula closed up temporarily.
The patient lived with her disease for 15 years and was still alive at the time of the interview. (Oncologist)
(v) One patient with advanced inoperable prostate cancer and bone metastases (one in the pelvis at a
size of 10 cm) received intravenous and partly intratumoral MT, and partly hormones and
chemotherapy; he survived 12 years. (Neurologist, intensive care specialist)
(vi) Another patient with prostate cancer and lymph node metastases had received hormone treatment
(bicalutamid, goserelin), which led to a reduction in PSA levels. After about 5 months, he engaged in a
new partnership and gave great importance to his sexual function and thus terminated hormone
treatment. After some months of increasing the PSA levels, an intravenous MT (Helixor M, 10–1500 mg)
was started, intensifying the previous standard subcutaneous application. This led to a stabilization of
PSA levels for 1 year. (Oncologist)
(vii) A patient had a rapidly growing glioblastoma at an initial size of 15 cm. Due to the rapid growth, the
patient’s first surgery was followed by re-surgery after only 2 weeks, and the subsequent radiotherapy
terminated after 4 weeks. As this point, the tumor was already larger than its size before the first
surgery. Mistletoe infusions were started and the situation stabilized. The patient lived for 1 more year.
(Neurologist, intensive care specialist)