Research Article

Evaluation of Toxicological Effects of an Aqueous Extract of Shells from the Pecan Nut Carya illinoinensis (Wangenh.) K. Koch and the Possible Association with Its Inorganic Constituents and Major Phenolic Compounds

Table 5

Biochemical analyses from mice treated with pecan shell aqueous extract (PSAE), ellagic acid (EA), and gallic acid (GA).

Treatment group Cholesterol (mg/dL)Triglycerides (mg/dL)Glucose (mg/dL)ALT (UI/L)

Vehicle111.1 ± 24.594.8 ± 24.298.1 ± 34.350.6 ± 28.7

PSAE 50 mg kg−1121.0 ± 4.873.2 ± 48.355.3 ± 38.673.1 ± 25.5
PSAE 100 mg kg−1147.4 ± 18.7102.8 ± 69.095.7 ± 53.770.1 ± 10.8
PSAE 200 mg kg−1142.5 ± 13.959.6 ± 16.658.1 ± 15.677.6 ± 43.2

EA 10 mg kg−1132.4 ± 38.748.5 ± 12.459.6 ± 12.833.7 ± 10.2
EA 50 mg kg−1142.5 ± 67.653.8 ± 14.251.6 ± 13.231.8 ± 7.2
EA 100 mg kg−1156.8 ± 73.248.1 ± 19.157.6 ± 21.841.5 ± 11.6

GA 10 mg kg−1137.4 ± 17.2105.9 ± 41.486.9 ± 20.742.6 ± 19.0
GA 50 mg kg−1120.6 ± 10.6144.4 ± 20.2142.7 ± 39.943.5 ± 1.8
GA 100 mg kg−1133.8 ± 25.2112.0 ± 30.296.1 ± 27.074.8 ± 61.0

Values are presented as mean and standard deviation.
: significant difference in comparison with the vehicle group (ANOVA, Dunnett’s test).