Metabolomic Analysis of Biochemical Changes in the Plasma of High-Fat Diet and Streptozotocin-Induced Diabetic Rats after Treatment with Isoflavones Extract of Radix Puerariae

Table 1

Effects of PTIF (421 mg/kg) on body weight in high-fat diet and STZ-induced diabetic rats (g).

Group		0 weeks	26 weeks	30 weeks	34 weeks	36 weeks
Normal	10	283.4 ± 7.8	522.2 ± 22.0	553.6 ± 24.4	586.2 ± 30.4	601.8 ± 30.5
Diabetic	10	280.1 ± 5.2	404.1 ± 49.6	375.3 ± 50.3	378.0 ± 54.8	386.4 ± 57.5
Diabetic + PTIF	9	285.3 ± 7.3	426.8 ± 39.5	406.8 ± 48.1	431.7 ± 48.0^#	438.9 ± 49.4^#

All data were expressed as mean ± SD. One-way analysis of variance (ANOVA) was used for significance analysis. and indicate a significant difference as compared with normal rats; ^# indicate a significant difference as compared with diabetic rats.