Acute and Subacute Toxicological Evaluation of the Aerial Extract of Monsonia angustifolia E. Mey. ex. A. Rich in Wistar Rats

Table 4

Effect of 28-day administration of Monsonia angustifolia extract on some kidney function parameters of Wistar rats.

Parameters	Control	Extract (mg/kg body weight)
		75	150	300
Creatinine (mg/dL)	28.00 ± 0.71	30.00 ± 2.83	29.00 ± 3.61	28.67 ± 2.52
Uric acid (mg/dL)	5.33 ± 0.15	5.43 ± 0.35	5.56 ± 0.31	5.70 ± 0.10
Urea (mg/dL)	7.33 ± 1.12	6.90 ± 2.59	6.83 ± 0.98	7.17 ± 0.76
Calcium (mg/dL)	8.13 ± 0.06	8.36 ± 0.21	8.33 ± 0.25	8.16 ± 0.12
Potassium (mmol/L)	5.20 ± 0.25	5.53 ± 3.14	5.20 ± 0.96	5.37 ± 0.21

Data are means ± SEM ( = 6). Values not carrying superscripts are not significantly different () from the control.