Polysaccharide Extracted from Laminaria japonica Delays Intrinsic Skin Aging in Mice

Figure 4

LP reverses the age-induced increase in JNK but not p38 MAPK signaling. Expression of p-JNK, JNK, p-p38, and p38 proteins in skin tissue of young control mice and aging mice without or with LP-L, LP-M, LP-H, and Vit. E treatment, as determined by western blotting. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) served as a loading control. Expression levels were quantified by densitometry. Values represent mean ± SD (). and versus aging model group.