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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 5616905, 7 pages
http://dx.doi.org/10.1155/2016/5616905
Research Article

Effect of Aurantii Fructus Immaturus Flavonoid on the Contraction of Isolated Gastric Smooth Muscle Strips in Rats

Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China

Received 15 February 2016; Revised 16 May 2016; Accepted 30 May 2016

Academic Editor: Jiande D. Z. Chen

Copyright © 2016 Zhenyu Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Tack, N. J. Talley, M. Camilleri et al., “Functional gastroduodenal disorders,” Gastroenterology, vol. 130, no. 5, pp. 1466–1479, 2006. View at Publisher · View at Google Scholar
  2. H. B. El-Serag and N. J. Talley, “The prevalence and clinical course of functional dyspepsia,” Alimentary Pharmacology & Therapeutics, vol. 19, no. 6, pp. 643–654, 2004. View at Publisher · View at Google Scholar
  3. L. Van Oudenhove, J. Vandenberghe, R. Vos, L. Holvoet, K. Demyttenaere, and J. Tack, “Risk factors for impaired health-related quality of life in functional dyspepsia,” Alimentary Pharmacology and Therapeutics, vol. 33, no. 2, pp. 261–274, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. R. A. Brook, N. L. Kleinman, S. R. Choung et al., “Functional dyspepsia impacts absenteeism and direct and indirect costs,” Clinical Gastroenterology and Hepatology, vol. 8, no. 6, pp. 498–503, 2010. View at Publisher · View at Google Scholar
  5. M. Camilleri, “Functional dyspepsia: mechanisms of symptom generation and appropriate management of patients,” Gastroenterology Clinics of North America, vol. 36, no. 3, pp. 649–664, 2007. View at Publisher · View at Google Scholar
  6. C. Wang, M. Zhu, W. Xia, W. Jiang, and Y. Li, “Meta-analysis of Traditional Chinese Medicine in treating functional dyspepsia of liver-stomach disharmony syndrome,” Journal of Traditional Chinese Medicine, vol. 32, no. 4, pp. 515–522, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. H. Wu, Z. Jing, X. Tang et al., “To compare the efficacy of two kinds of Zhizhu pills in the treatment of functional dyspepsia of spleen-deficiency and qi-stagnation syndrome: a randomized group sequential comparative trial,” BMC Gastroenterology, vol. 11, article 81, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. Y.-S. Fang, D.-M. Shan, J.-W. Liu et al., “Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement,” Planta Medica, vol. 75, no. 1, pp. 24–31, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Huang, Y. Chi, Y. Zeng, and L. Lu, “Influence of fructus aurantii immaturus flavonoids on gastrointestinal motility in rats with functional dyspepsia,” Traditional Chinese Drug Research & Clinical Pharmacology, vol. 23, pp. 612–615, 2012. View at Google Scholar
  10. T.-Z. Zheng, W. Li, S.-Y. Qu, Y.-M. Ma, Y.-H. Ding, and Y.-L. Wei, “Effects of Dangshen on isolated gastric muscle strips in rats,” World Journal of Gastroenterology, vol. 4, no. 1–6, pp. 354–356, 1998. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Yang, S.-S. Zhang, X.-L. Li, Z.-F. Wang, and L.-Q. Zhao, “Inhibitory effect of TongXie-YaoFang formula on colonic contraction in rats,” World Journal of Gastroenterology, vol. 21, no. 10, pp. 2912–2917, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Yu, Y.-L. Luo, J.-W. Zheng et al., “Effects of rhubarb on isolated gastric muscle strips of guinea pigs,” World Journal of Gastroenterology, vol. 11, no. 17, pp. 2670–2673, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. Z. H. Huang, D. Z. Yang, and Y. Q. Wei, “Effect of atropine on the enhancing action of Fructus Aurantii Immaturus on the myoelectric activity of small intestine in dogs,” Chinese Journal of Integrated Traditional and Western Medicine, vol. 16, no. 5, pp. 292–294, 1996. View at Google Scholar · View at Scopus
  14. Z. Tianzhen, L. Wei, Q. Songyi, D. Yonghui, and W. Yuling, “Action of traditional Chinese medicines of Zhishi and Baizhu on contractile activity of isolated gastric muscular strips in rats,” Journal of Gansu Sciences, vol. 10, pp. 66–68, 1998. View at Google Scholar
  15. H. Miwa, “Why dyspepsia can occur without organic disease: pathogenesis and management of functional dyspepsia,” Journal of Gastroenterology, vol. 47, no. 8, pp. 862–871, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. A. E. Bharucha, A. Manduca, D. S. Lake et al., “Gastric motor disturbances in patients with idiopathic rapid gastric emptying,” Neurogastroenterology & Motility, vol. 23, no. 7, pp. 617–e252, 2011. View at Publisher · View at Google Scholar
  17. C. A. Paterson, M. Anvari, G. Tougas, and J. D. Huizinga, “Determinants of occurrence and volume of transpyloric flow during gastric emptying of liquids in dogs: importance of vagal input,” Digestive Diseases and Sciences, vol. 45, no. 8, pp. 1509–1516, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. Giulir, T. R. Demester, and R. Leven, “Surgical complication and reasons for failure,” in Cancer of the Esophagus, pp. 199–208, Grune & Stratratton Inc, Orlando, Fla, USA, 1985. View at Google Scholar
  19. F. E. Lüdtke, E. Lammel, K. Mandrek, H. J. Peiper, and K. Golenhofen, “Myogenic basis of motility in the pyloric region of human and canine stomachs,” Digestive Diseases, vol. 9, no. 6, pp. 414–431, 1991. View at Google Scholar · View at Scopus
  20. D. Ramkumar and K. S. Schulze, “The pylorus,” Neurogastroenterology and Motility, vol. 17, no. 1, pp. 22–30, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Wenhai, W. Xinzeng, W. Zhenghua, L. Zhongchang, and Z. Xia, “Effect of iron deficiency on gastric emptying function of rats and its mechanism,” Journal of the Fourth Military Medical University, vol. 20, pp. 756–758, 1999. View at Google Scholar
  22. C. Jiayi, Study on PK and PD in Irritable Bowel Syndrome with Syndrome of Liver Invading the Spleen of Extract from Citrus Aurantium, Guangzhou University of Chinese Medicine, Guangzhou, China, 2014.
  23. M. Anvari, C. A. Paterson, and E. E. Daniel, “Role of nitric oxide mechanisms in control of pyloric motility and transpyloric flow of liquids in conscious dogs,” Digestive Diseases and Sciences, vol. 43, no. 3, pp. 506–512, 1998. View at Publisher · View at Google Scholar · View at Scopus
  24. D. Yu, J. Jun, T. Kim, D. Suh, D. Youn, and T. Kim, “The relaxing effect of Poncirus fructus and its flavonoid content on porcine coronary artery,” Laboratory Animal Research, vol. 31, no. 1, pp. 33–39, 2015. View at Publisher · View at Google Scholar