Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways

<div>The inhibitory effects of spent coffee grounds SFE on melanogenesis. (a) The effects of spent coffee grounds SFE on mushroom tyrosinase activity. (b) The effects of spent coffee grounds SFE on melanin content in B16F10 cells. (c) The effects of spent coffee grounds SFE on tyrosinase activity in B16F10 cells. The results are presented as percentages of the control, and the data are presented as the mean ± SD of three separate experiments. 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Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways 

Figure 2 | Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways 