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Evidence-Based Complementary and Alternative Medicine
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Evidence-Based Complementary and Alternative Medicine
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2016
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Article
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Tab 3
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Research Article
A Novel Method for Evaluating the Cardiotoxicity of Traditional Chinese Medicine Compatibility by Using Support Vector Machine Model Combined with Metabonomics
Table 3
Content change trend of early cardiac toxicity biomarkers.
(min)
Metabolite
Content change
Identified
HSP
GL
ZBM
BL
BJ
HSP + GL
HSP + ZBM
HSP + BL
HSP + BJ
0.76
162.1123
L-carnitine
↑
↑
↓
↑
↑
↓
↑
↑
↑
↑
4.19
190.0863
↓
↓
↓
↓
↓
↓
↓
↓
↓
↓
4.19
172.0755
↓
↓
↓
↓
↓
↓
↓
↓
↓
↓
4.19
130.065
↓
↓
↑
↓
↓
↓
↓
↓
↓
↓
4.67
347.2214
19-Hydroxydeoxycorticosterone
↓
↓
↑
↓
↓
↓
↓
↓
↓
↓
5.45
432.3107
↓
↓
↓
↓
↓
↓
↓
↓
↓
↓
5.87
299.2002
↓
↓
↓
↓
↓
↓
↓
↓
↓
↓
7.30
468.3467
↓
↓
↓
↓
↓
↓
↓
↓
↓
↓
7.85
548.3715
LPC (20:2)
↓
↓
↓
↓
↓
↓
↓
↓
↓
↓
6.48
490.2913
LPC (14:0)
↓
↓
↓
↓
↓
↓
↓
↓
↓
↓