Review Article

Application of Traditional Chinese Medical Herbs in Prevention and Treatment of Respiratory Syncytial Virus

Table 6

The mechanisms of TCMHs-based prevention and treatment of RSV.

PreventionTreatment

Viral attachment ↓ [1, 24, 29, 32, 6870]; 
viral internalization ↓ [1, 24, 29, 32, 6870]
RSV entry ↓ [24, 3249]

IFN-β, TNF-α production → viral replication ↓[1, 24, 29, 32, 54, 69, 70]RSV replication ↓ [3249, 5155, 57]

IFN-γ production → RSV viral infection ↓ [30, 31, 50, 57, 67]Syncytium formation of RSV ↓ [26]

The survival of human lung epithelial cells ↑ [31]Lung inflammation ↓ [30, 5052, 5456, 67, 68]

Activate the immune system [30, 50, 57]F protein expression of RSV ↓ [50]

Blocked proinflammatory gene expression [31, 54, 68] 
(in the human alveolar epithelial cell line)
Viral loads in serum and lung tissue ↓ [5154, 67]; 
no adverse reaction was found [53, 55]