Myricitrin Protects against Doxorubicin-Induced Cardiotoxicity by Counteracting Oxidative Stress and Inhibiting Mitochondrial Apoptosis via ERK/P53 Pathway

Figure 10

Effects of myricitrin on antitumor ability of Dox in vitro. Various cancer cell lines including HepG2 (a), Hep2 (b), and MCF-7 (c) cells were treated with Dox (1 μM) in presence or absence of 25 μg/mL myricitrin for 12 h prior to exposure to Dox for 36 h. The cell viability was measured by CCK8 assay. All data are expressed as the means ± SD (). versus Cont; versus Dox-treated cells.

(a)

(b)

(c)