Research Article
Effect of Alkaloids Isolated from Phyllodium pulchellum on Monoamine Levels and Monoamine Oxidase Activity in Rat Brain
Table 1
Effects of P. pulchellum alkaloids administered p.o. in mice.
| | Dose (mg/kg) | Obituary/total animals | Mortality (%) | Mortality latency (h) | LD50 (mg/kg) |
| | 6000 | 0/10 | 0 | — | 11300 | | 8000 | 2/10 | 20 | >72, <120 | | 11000 | 5/10 | 50 | >24, <48 | | 15000 | 7/10 | 70 | >24, <48 | | 20000 | 10/10 | 100 | >2, <24 |
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