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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 6872890, 12 pages
http://dx.doi.org/10.1155/2016/6872890
Research Article

Exploratory Factor Analysis for Validating Traditional Chinese Syndrome Patterns of Chronic Atrophic Gastritis

1Beijing University of Chinese Medicine, Chaoyang District, Beijing 100029, China
2Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Dongcheng District, Beijing 100700, China
3School of Humanities, Beijing University of Chinese Medicine, Chaoyang District, Beijing 100029, China
4Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Chaoyang District, Beijing 100029, China
5Department of Neurosurgery, China-Japan Friendship Hospital, Chaoyang District, Beijing 100029, China
6Institute of Systems Engineering, Faculty of Management and Economics, Dalian University of Technology, Ganjingzi District, Dalian 116024, China
7Department of Gastroenterology, China-Japan Friendship Hospital, Beijing 100029, China
8Department of Pathology, China-Japan Friendship Hospital, Chaoyang District, Beijing 100029, China
9Department of General Surgery, China-Japan Friendship Hospital, Chaoyang District, Beijing 100029, China
10Department of Thoracic Surgery, China-Japan Friendship Hospital, Chaoyang District, Beijing 100029, China

Received 30 July 2016; Accepted 31 October 2016

Academic Editor: Giuseppe Caminiti

Copyright © 2016 Yin Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Traditional Chinese medicine (TCM) has long been used to treat chronic atrophic gastritis (CAG). The aim of the present study was to evaluate the TCM syndrome characteristics of CAG and its core pathogenesis so as to promote optimization of treatment strategies. Methods. This study was based on a participant survey conducted in 4 hospitals in China. Patients diagnosed with CAG were recruited by simple random sampling. Exploratory factor analysis (EFA) was conducted on syndrome extraction. Results. Common factors extracted were assigned to six syndrome patterns: qi deficiency, qi stagnation, blood stasis, phlegm turbidity, heat, and yang deficiency. Distribution frequency of all syndrome patterns showed that qi deficiency, qi stagnation, blood stasis, phlegm turbidity, and heat excess were higher (76.7%–84.2%) compared with yang deficiency (42.5%). Distribution of main syndrome patterns showed that frequencies of qi deficiency, qi stagnation, phlegm turbidity, heat, and yang deficiency were higher (15.8%–20.8%) compared with blood stasis (8.3%). Conclusions. The core pathogenesis of CAG is combination of qi deficiency, qi stagnation, blood stasis, phlegm turbidity, heat, and yang deficiency. Therefore, treatment strategy of herbal prescriptions for CAG should include herbs that regulate qi, activate blood, resolve turbidity, clear heat, remove toxin, and warm yang.