Research Article

Du-Huo-Ji-Sheng-Tang Attenuates Inflammation of TNF-Tg Mice Related to Promoting Lymphatic Drainage Function

Figure 4

Impaired lymphatic function of TNF-Tg mice was rescued by Du-Huo-Ji-Sheng-Tang. Three-month-old TNF-Tg mice were treated with Du-Huo-Ji-Sheng-Tang or saline for 12 weeks and were subjected to ICG-NIR imagining. (a) Representative ICG images show that Du-Huo-Ji-Sheng-Tang increased ICG removal from ankle area. (b) Quantitation of % ICG clearance. Values are mean ± SD of 8–18 legs. (c) Lymphatic pulses were measured at a region of interest. Histogram shows that Du-Huo-Ji-Sheng-Tang restored lymphatic pulses in TNF-Tg mice. (d) Quantitation of lymphatic pulses/min. Values are mean ± SD of 7–18 legs from 4–9 mice. versus WT mice, versus saline treated TNF-Tg group.
(a)
(b)
(c)
(d)