Table 2: The MIC values of aqueous and methanol extracts of miswak against 10 MDR pathogenic organisms.

MDR bacterial
isolates
MIC values (mg/mL)MIC values (µg/mL)
Miswak extractsPositive control
AqueousMethanolVANTOB

MRSA12.56.251.0NT
MRSE6.253.1250.5NT
Streptococcus pyogenes1.561.560.125NT
E. faecalis3.1253.1250.5NT
E. coli1.560.39NT0.25
K. pneumonia3.1250.781NT0.5
P. aeruginosa6.251.56NT1.0
S. marcescens1.561.56NT2.0
A. baumannii12.56.25NT8.0
S. maltophilia12.56.25NT4.0

MRSA: methicillin-resistant staphylococcus aureus, MRSE: methicillin-resistant staphylococcus epidermidis.
VAN: vancomycin, TOB: tobramycin, and NT: not tested.
The CLSI MIC Interpretive Criteria for vancomycin (VAN): ≤2 µg/mL: Susceptible, 4–8 µg/mL: Intermediate, ≥16 µg/mL: Resistant [21].
The CLSI MIC interpretive criteria for tobramycin (TOB): ≤4 ug/mL: susceptible, 8 µg/mL: intermediate, and ≥16 µg/mL: resistant [21].