Ex Vivo Stromal Cell-Derived Factor 1-Mediated Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells into Hepatocytes Is Enhanced by Chinese Medicine Yiguanjian Drug-Containing Serum

Table 3

Cytokeratin-18 (CK-18) in P2 BM-derived MSCs determined by ICC.

	CK-18^+ BM-derived MSCs (%)
	7 days	14 days	21 days	28 days
Negative controls	0	0	0	0
HGF + normal serum	0	42.19 ± 3.78	47.46 ± 2.75	68.61 ± 1.23^△
HGF + SDF-1 + normal serum	34.00 ± 1.85	47.68 ± 1.75	50.55 ± 1.01	72.45 ± 4.01^△
HGF + SDF-1 + YGJ	45.76 ± 2.20	56.24 ± 3.51	71.36 ± 1.02	76.72 ± 2.18^△
YGJ	4.05 ± 1.28	11.25 ± 2.31^#	18.92 ± 1.89^#	21.21 ± 3.27

Note. Data are shown as mean ± SD from 5 independent experiments. HGF + SDF-1 + Yiguanjian drug serum versus HGF + SDF-1 + normal serum at the same time point. : 28 days versus 7 days under the same induction condition. : 14 days versus 7 days and 21 days versus 14 days.