Diosgenin and 5-Methoxypsoralen Ameliorate Insulin Resistance through ER-α/PI3K/Akt-Signaling Pathways in HepG2 Cells

Figure 8

Effects of DSG and 5-MOP on expression of GLUT-4 (green) in HepG2 cells. Nuclei were also stained with DAPI (blue). Immunofluorescence showed that (c) DSG, (d) 5-MOP, (e) DSG + 5-MOP, and (f) β-Estradiol led to an increase of the GLUT-4 expression compared with the (b) model group. Each bar represents mean ± SD from three wells. : significance from control group. and : significance from model group. : significance from 5-MOP-treated group.