Research Article

The Relieving Effects of BrainPower Advanced, a Dietary Supplement, in Older Adults with Subjective Memory Complaints: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 5

(a) Distribution of subjective attention deficit (SAD) symptom severity (using a 5-point questionnaire) in older adults before and after BrainPower Advanced or placebo intervention. (b) Ridit scoring test of the ranked data showed that more people in the BrainPower Advanced group showed reduced SAD (−) and fewer people in the BrainPower Advanced group showed no change or worsened SAD than people in the placebo group after the interventions (). (c) McNemar’s test of the combined data (2 scales) of subjective attention deficit (SAD) shows that BrainPower Advanced intervention, but not placebo intervention, reversed a significantly greater proportion of severe SAD in the older adults. It was noted, however, that BrainPower Advanced group had more severe cases and fewer mild cases of SAD than the placebo group before the intervention.
(a)

Distribution of SAD symptom severity
Group 1, none or slight2, mild3, moderate4, severe5, very severe

Before interventionBrainPower group1 (2.1%)3 (6.4%)16 (34.0%)19 (40.4%)8 (17.0%)
Placebo group7 (13.7%)7 (13.7%)8 (15.7%)22 (43.1%)7 (13.7%)
Total8 (8.2%)10 (10.2%)24 (24.5%)41 (41.8%)15 (15.3%)

After interventionBrainPower group4 (8.5%)15 (31.9%)21 (44.7%)6 (12.8%)1 (2.1%)
Placebo group2 (3.9%)17 (33.3%)16 (31.4%)15 (29.4%)1 (2.0%)
Total 6 (6.1%)32 (32.7%)37 (37.8%)21 (21.4%)2 (2.0%)

(b)

Symptom score change⁢BrainPower group⁢Placebo groupTotal

−324.323.944.1
−21429.8815.72222.4
−12042.61019.63030.6
0919.11529.41414.3
+124.31121.61313.3
+200.035.933.1
+300.023.922.0
Total47100.051100.098100.0

(c)

Treatment group Before interventionAfter intervention value of McNemar’s test
No or slightSevereNo or slightSevere

BrainPower group4 (8.5%)43 (91.5%)19 (40.4%)28 (59.6%)0.001
Placebo group14 (27.5%)37 (72.5%)19 (37.3%)32 (62.7%)0.302
Pearson 5.8520.104
0.0160.748