Research Article

Effect of Heweianshen Decoction on Orexin-A and Cholecystokinin-8 Expression in Rat Models of Insomnia

Table 3

Effect of the Heweianshen decoction on CCK-8 levels in hypothalamus of rat model of insomnia ().

GroupCCK-8 (pg/mg)

Blank group101.97 ± 0.54
PCPA model group101.12 ± 0.41
Low-dose group101.34 ± 0.23
Medium-dose group101.68 ± 0.39
High-dose group101.82 ± 0.67

Notes: blank group and model group were given normal saline 1 mL/100 g; the low-, medium-, and high-dose HAD-treated groups were given Heweianshen decoction of 5.25, 10.5, and 21 g⋅kg−1⋅d−1, respectively. Compared with the blank group, ; compared with the model group, ; compared with the model group, .