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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 8473937, 12 pages
http://dx.doi.org/10.1155/2016/8473937
Research Article

Bee Pollen as a Promising Agent in the Burn Wounds Treatment

1Department of Community Pharmacy, School of Pharmacy and Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, Kasztanowa 3, 41-200 Sosnowiec, Poland
2Department of Biomedical Computer Systems, Faculty of Computer Science and Materials Science, Institute of Computer Science, University of Silesia, Bedzinska 39, 41-200 Sosnowiec, Poland
3Department of Clinical Chemistry and Laboratory Diagnostics, School of Pharmacy and Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, Jednosci 8, 41-200 Sosnowiec, Poland
4Department and Institute of Microbiology and Virology, School of Pharmacy and Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, Jagiellonska 4, 41-200 Sosnowiec, Poland
5Center of Experimental Medicine, Medics 4, Faculty of Medicine in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, Poland

Received 10 February 2016; Revised 18 April 2016; Accepted 24 April 2016

Academic Editor: José Maurício Sforcin

Copyright © 2016 Paweł Olczyk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Velnar, T. Bailey, and V. Smrkolj, “The wound healing process: an overview of the cellular and molecular mechanisms,” Journal of International Medical Research, vol. 37, no. 5, pp. 1528–1542, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. D. D. S. Tavares Pereira, M. H. M. Lima-Ribeiro, N. T. De Pontes-Filho, A. M. D. A. Carneiro-Leão, and M. T. D. S. Correia, “Development of animal model for studying deep second-degree thermal burns,” Journal of Biomedicine and Biotechnology, vol. 2012, Article ID 460841, 7 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Sinno and S. Prakash, “Complements and the wound healing cascade: an updated review,” Plastic Surgery International, vol. 2013, Article ID 146764, 7 pages, 2013. View at Publisher · View at Google Scholar
  4. G. Gethin, “Understanding the inflammatory process in wound healing,” British Journal of Community Nursing, vol. 17, no. 3, pp. S17–S22, 2012. View at Google Scholar · View at Scopus
  5. J. M. Reinke and H. Sorg, “Wound repair and regeneration,” European Surgical Research, vol. 49, no. 1, pp. 35–43, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. A. K. Kuropatnicki, E. Szliszka, and W. Krol, “Historical aspects of propolis research in modern times,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 964149, 11 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. M. R. Campos, S. Bogdanov, L. M. de Almeida-Muradian, T. Szczesna, Y. Mancebo, and C. Frigerio, “Pollen composition and standardisation of analytical methods,” Journal of Apicultural Research and Bee World, vol. 47, no. 2, pp. 156–163, 2008. View at Google Scholar
  8. E. Szliszka and W. Krol, “Polyphenols isolated from propolis augment TRAIL-induced apoptosis in cancer cells,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 731940, 10 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. B. Kedzia, “Chemical composition of Polish propolis. Part I. The initial period of investigations,” Postepy Fitoterapii, vol. 10, no. 1, pp. 39–44, 2009. View at Google Scholar
  10. A. Rzepecka-Stojko, B. Pilawa, P. Ramos, and J. Stojko, “Antioxidative properties of bee pollen extracts examined by EPR spectroscopy,” Journal of Apicultural Science, vol. 56, no. 1, pp. 23–31, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. B. Kedzia and E. Holderna-Kedzia, “Właściwości biologiczne i działanie lecznicze pyłku kwiatowego zbieranego przez pszczoły,” Postepy Fitoterapii, vol. 3, pp. 103–108, 2005. View at Google Scholar
  12. M. Hellner, D. Winter, R. Von Georgi, and K. Münstedt, “Apitherapy: usage and experience in German beekeepers,” Evidence-Based Complementary and Alternative Medicine, vol. 5, no. 4, pp. 475–479, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Pietrusa and K. Derbisz, “Produkty pszczele część II: pyłek pszczeli,” Przeglad Urologiczny, vol. 6, no. 94, pp. 48–50, 2015. View at Google Scholar
  14. C. Nogueira, A. Iglesias, X. Feás, and L. M. Estevinho, “Commercial bee pollen with different geographical origins: a comprehensive approach,” International Journal of Molecular Sciences, vol. 13, no. 9, pp. 11173–11187, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. O. Brandt, M. Mildner, A. E. Egger et al., “Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine,” Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 8, no. 4, pp. 478–488, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. G. Sandri, M. C. Bonferoni, F. D'Autilia et al., “Wound dressings based on silver sulfadiazine solid lipid nanoparticles for tissue repairing,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 84, no. 1, pp. 84–90, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. M. J. Hoekstra, P. Hupkens, R. P. Dutrieux, M. M. C. Bosch, T. A. Brans, and R. W. Kreis, “A comparative burn wound model in the New Yorkshire pig for the histopathological evaluation of local therapeutic regimens: silver sulfadiazine cream as a standard,” British Journal of Plastic Surgery, vol. 46, no. 7, pp. 585–589, 1993. View at Publisher · View at Google Scholar · View at Scopus
  18. T. A. Brans, R. P. Dutrieux, M. J. Hoekstra, R. W. Kreis, and J. S. du Pont, “Histopathological evaluation of scalds and contact burns in the pig model,” Burns, vol. 20, no. 1, pp. S48–S51, 1994. View at Publisher · View at Google Scholar · View at Scopus
  19. M. K. York, “Aerobic Bacteriology. Quantitative cultures of wound tissues,” in Clinical Microbiology Procedures Handbook, H. D. Isenberg, Ed., section 3.13.2, ASM Press, Washington, DC, USA, 2nd edition, 2004. View at Google Scholar
  20. I. I. A. Darby, B. Laverdet, F. Bonté, and A. Desmoulière, “Fibroblasts and myofibroblasts in wound healing,” Clinical, Cosmetic and Investigational Dermatology, vol. 7, pp. 301–311, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. P. Olczyk, K. Komosinska-Vassev, K. Winsz-Szczotka, J. Stojko, K. Klimek, and E. M. Kozma, “Propolis induces chondroitin/dermatan sulphate and hyaluronic acid accumulation in the skin of burned wound,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 290675, 8 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Olczyk, K. Komosinska-Vassev, K. Winsz-Szczotka et al., “Propolis modulates vitronectin, laminin, and heparan sulfate/heparin expression during experimental burn healing,” Journal of Zhejiang University: Science B, vol. 13, no. 11, pp. 932–941, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. P. Olczyk, G. Wisowski, K. Komosinska-Vassev et al., “Propolis modifies collagen types I and III accumulation in the matrix of burnt tissue,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 423809, 10 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. P. Olczyk, P. Ramos, K. Komosińska-Vassev, J. Stojko, and B. Pilawa, “Positive effect of propolis on free radicals in burn wounds,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 356737, pp. 1–12, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. T. Dai, Y.-Y. Huang, S. K. Sharma, J. T. Hashmi, D. B. Kurup, and M. R. Hamblin, “Topical antimicrobials for burn wound infections,” Recent Patents on Anti-Infective Drug Discovery, vol. 5, no. 2, pp. 124–151, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. F. W. Fuller, “The side effects of silver sulfadiazine,” Journal of Burn Care and Research, vol. 30, no. 3, pp. 464–470, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. U. Czyewska, J. Konończuk, J. Teul et al., “Verification of chemical composition of commercially available propolis extracts by gas chromatography-mass spectrometry analysis,” Journal of Medicinal Food, vol. 18, no. 5, pp. 584–591, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. Y. Nakajima, K. Tsuruma, M. Shimazawa, S. Mishima, and H. Hara, “Comparison of bee products based on assays of antioxidant capacities,” BMC Complementary and Alternative Medicine, vol. 9, article 4, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. V. Jayarama Reddy, S. Radhakrishnan, R. Ravichandran et al., “Nanofibrous structured biomimetic strategies for skin tissue regeneration,” Wound Repair and Regeneration, vol. 21, no. 1, pp. 1–16, 2013. View at Publisher · View at Google Scholar · View at Scopus
  30. P. Olczyk, I. Wróblewska-Adamek, J. Stojko, K. Komosińska-Vassev, and K. Olczyk, “Histopathological evaluation of Propol-T and silver sulfadiazine therapeutic efficacy in burn healing,” Farmacja Polska, vol. 63, no. 24, pp. 1108–1116, 2007. View at Google Scholar
  31. Ż. Jastrzębska-Stojko, R. Stojko, A. Rzepecka-Stojko, A. Kabała-Dzik, and J. Stojko, “Biological activity of propolis-honey balm in the treatment of experimentally-evoked burn wounds,” Molecules, vol. 18, no. 11, pp. 14397–14413, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. A. Kabała-Dzik, E. Szaflarska-Stojko, R. D. Wojtyczka et al., “Efficiency assessment of antimicrobial activity of honey-balm on experimental burn wounds,” Bulletin of the Veterinary Institute in Pulawy, vol. 48, no. 2, pp. 109–112, 2004. View at Google Scholar · View at Scopus
  33. M. Morais, L. Moreira, X. Feás, and L. M. Estevinho, “Honeybee-collected pollen from five Portuguese Natural Parks: Palynological origin, phenolic content, antioxidant properties and antimicrobial activity,” Food and Chemical Toxicology, vol. 49, no. 5, pp. 1096–1101, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Rzepecka-Stojko, J. Stojko, A. Kurek-Górecka et al., “Polyphenols from bee pollen: structure, absorption, metabolism and biological activity,” Molecules, vol. 20, no. 12, pp. 21732–21749, 2015. View at Publisher · View at Google Scholar
  35. N. B. Takaisi-Kikuni and H. Schilcher, “Electron microscopic and microcalorimetric investigations of the possible mechanism of the antibacterial action of a defined propolis provenance,” Planta Medica, vol. 60, no. 3, pp. 222–227, 1994. View at Publisher · View at Google Scholar · View at Scopus