Veratri Nigri Rhizoma et Radix (Veratrum nigrum L.) and Its Constituent Jervine Prevent Adipogenesis via Activation of the LKB1-AMPKα-ACC Axis In Vivo and In Vitro

Figure 5

Effect of VN on adipogenesis-related factors in 3T3-L1 adipocytes. The mRNA expression levels of (a) PPARγ and C/EBPα, (c) aP2, adiponectin, and resistin, and (d) LIPIN1 were measured by the Real-Time RT-PCR assays. (b) The expressions PPARγ and C/EBPα were measured using a Western blot assay. GAPDH was used as an endogenous control. EGCG was used as a positive control. Data are expressed as mean ± SD of three or more experiments. versus MDI-uninduced preadipocytes, , and versus MDI-induced adipocytes.

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