The Effects of Xiangqing Anodyne Spray on Treating Acute Soft-Tissue Injury Mainly Depend on Suppressing Activations of AKT and p38 Pathways

Figure 1

Effect of XQAS on muscle swelling rate (MSR) in the acute STI model induced by hitting hind leg muscle in rats. The rats were no modeling topically repeatedly treated with 150 μL/time vehicles in the control (Ctrl), or modeling topically repeatedly treated with 150 μL/time vehicles in the acute STI model (Mod), XQAS in the high-dose and low-dose XQAS-treated group (HXQAS and LXQAS, containing 0.50 or 0.25 g/mL both CP and IH, resp.), CPS (containing 1.0 g/mL CP) (CPS), or IHS (containing 1.0 g/mL IH) (IHS) for 8 h. The data were shown as mean ± SD ( per group). aa: versus Ctrl; b: , or bb: versus Mod. c: , or cc: versus HXQAS.