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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 9240103, 10 pages
Research Article

Identification of the Metabolic Enzyme Involved Morusin Metabolism and Characterization of Its Metabolites by Ultraperformance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS/MS)

1Department of Pharmacy, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China
2Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA, USA
3Department of Internal Medicine/Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada
4Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China

Received 12 May 2016; Revised 27 July 2016; Accepted 2 August 2016

Academic Editor: Con Stough

Copyright © 2016 Xianbao Shi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [2 citations]

The following is the list of published articles that have cited the current article.

  • Chuqi Hou, Wenqin Liu, Zhi Liang, Weichao Han, Jinqing Li, Ling Ye, Menghua Liu, Zheng Cai, Jie Zhao, Yi Chen, Shuwen Liu, and Lan Tang, “UGT-mediated metabolism plays a dominant role in the pharmacokinetic behavior and the disposition of morusin in vivo and in vitro,” Journal of Pharmaceutical and Biomedical Analysis, 2018. View at Publisher · View at Google Scholar
  • Petruta Aelenei, Simon Vlad Luca, Cristina Elena Horhogea, Cristina Mihaela Rimbu, Gabriel Dimitriu, Irina Macovei, Mihaela Silion, Ana Clara Aprotosoaie, and Anca Miron, “Morus alba leaf extract: Metabolite profiling and interactions with antibiotics against Staphylococcus spp. including MRSA,” Phytochemistry Letters, vol. 31, pp. 217–224, 2019. View at Publisher · View at Google Scholar