Table 3: Semiquantitative scoring of the architectural changes evidenced by histopathological examination of the rats’ livers and kidneys.

Scoring parameterGroup
1234567

Liver
Degeneration of hepatocytes+++++++++
Inflammatory cell infiltration+++++++++
Vascular congestion+++++++
Edema+++++++++

Kidney
Tubular necrosis+++++++++
Vacuolization++++++++
Glomerular necrosis++++++++++

Scoring was performed as follows: none (—), mild (+), moderate (++), and severe (+++).
Group 1 = control; Group 2 = EECM; Group 3 = APAP; Group 4 = T 250; Group 5 = T 500; Group 6 = T 1000; and Group 7 = silymarin.