Ilexonin A Promotes Neuronal Proliferation and Regeneration via Activation of the Canonical Wnt Signaling Pathway after Cerebral Ischemia Reperfusion in Rats

Figure 4

Effect of IA on GSK3β protein and Axin mRNA expression detected by western blotting and RT-PCR with β-actin protein as a reference. Lane 1: control; Lane 2: sham; Lane 3: model 1 d; Lane 4: IA 1 d; Lane 5: model 3 d; Lane 6: IA 3 d; Lane 7: model 7 d; Lane 8: IA 7 d; Lane 9: model 14 d; Lane 10: IA 14 d. (a) The expression of GSK3β declined after IA treatment compared with model group at corresponding point in time. (b) Quantitative analysis of GSK3β protein. compared with model group at corresponding point in time. (c) The expression of Axin mRNA declined after IA treatment compared with model group at corresponding point in time. (d) Quantitative analysis of Axin mRNA. compared with model group at corresponding point in time.

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