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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 1053617, 10 pages
Review Article

The Versatile Effects of Dihydromyricetin in Health

1College of Pharmacy, Gannan Medical University, Ganzhou 341000, China
2Jiangxi Health Vocational College, Nanchang 330052, China

Correspondence should be addressed to Qilai Cheng; moc.621@75_lqc and Longhuo Wu; moc.liamtoh@uwhgnol

Received 24 May 2017; Accepted 27 July 2017; Published 30 August 2017

Academic Editor: Siyaram Pandey

Copyright © 2017 Hongliang Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Dihydromyricetin is a flavonoid isolated from Ampelopsis grossedentata, which is traditionally used in China. Dihydromyricetin exhibits health-benefiting activities with minimum adverse effects. Dihydromyricetin has been demonstrated to show antioxidative, anti-inflammatory, anticancer, antimicrobial, cell death-mediating, and lipid and glucose metabolism-regulatory activities. Dihydromyricetin may scavenge ROS to protect against oxidative stress or potentiate ROS generation to counteract cancer cells selectively without any effects on normal cells. However, the low bioavailability of dihydromyricetin limits its potential applications. Recent research has gained positive and promising data. This review will discuss the versatile effects and clinical prospective of dihydromyricetin.