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Evidence-Based Complementary and Alternative Medicine
Volume 2017, Article ID 1390301, 11 pages
https://doi.org/10.1155/2017/1390301
Review Article

Effectiveness and Safety of the Combination of the Traditional Chinese Medicine Prescription Jade Screen and Desloratadine in the Treatment of Chronic Urticaria: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

1Pharmaceutical Department, The Second Affiliated Hospital of Baotou Medical College, No. 30 Hudemulin Road, Baotou, Inner Mongolia 014030, China
2Pharmaceutical Department, Inner Mongolia International Mongolian Hospital, No. 83 Daxue East Road, Hohhot, Inner Mongolia 010065, China
3Dermatological Department, The Second Affiliated Hospital of Baotou Medical College, No. 30 Hudemulin Road, Baotou, Inner Mongolia 014030, China
4Department of Gastroenterology, The Second Affiliated Hospital of Baotou Medical College, No. 30 Hudemulin Road, Baotou, Inner Mongolia 014030, China
5Human Anatomy and Tissue Embryology, Weifang Medical University, No. 7166 Baotong Street, Weicheng District, Weifang, Shandong 261021, China
6Development Department, Inner Mongolia International Mongolian Hospital, No. 83 Daxue East Road, Hohhot, Inner Mongolia 010065, China

Correspondence should be addressed to Ji-hai Shi; moc.361@hmimi_ihsiahij

Received 15 June 2017; Revised 3 October 2017; Accepted 17 October 2017; Published 12 November 2017

Academic Editor: Subash C. Gupta

Copyright © 2017 Shao-fei Yuan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. The aim of this study is to systematically evaluate the clinical efficacy and safety of the traditional Chinese medicine prescription Jade Screen combined with desloratadine in the treatment of chronic urticaria. Methods. Two researchers independently conducted literature searches. The extracted data were analyzed using Rev Man 5.2.3 software. The established retrieval time range of the various databases was up to 15 March, 2017. Results. Sixteen randomized controlled trials were included in this study. The results of the meta-analysis showed that the total effective rate of using Jade Screen and desloratadine in combination to treat chronic urticaria was higher than that with desloratadine alone (), while its recurrence rate () and symptom score () were both significantly lower than the latter. The rate of adverse reaction in the combination group was lower than that when orally taking desloratadine alone (), and the serum level of total IgE in the combination group was lower than that when orally taking desloratadine alone (); however, the results of the rate of adverse reaction and the serum level of total IgE were insignificant. Conclusion. Using Jade Screen and desloratadine together to treat chronic urticaria gains a better clinical effect than using desloratadine alone.