iTRAQ-Based Proteomics of Chronic Renal Failure Rats after FuShengong Decoction Treatment Reveals Haptoglobin and Alpha-1-Antitrypsin as Potential Biomarkers
Table 1
Differentially expressed proteins among control, model, and FSGD groups obtained by iTRAQ-nanoHPLC-MS/MS. 113: control; 114: model; 115: FSGD; —: ratio between 0.83 and 1.20.
Protein ID
Protein name
115:114
114:113
115:113
sp∣P06866
Haptoglobin
0.10
12.62
1.74
sp∣P04639
Apolipoprotein A-I
0.17
4.90
—
sp∣Q6P734
Plasma protease C1 inhibitor
0.19
1.80
0.32
sp∣P02651
Apolipoprotein A-IV
0.23
2.28
0.52
sp∣P02764
Alpha-1-acid glycoprotein
0.25
1.87
0.45
sp∣P09006
Serine protease inhibitor A3N
0.28
1.71
0.48
tr∣D4A183
Protein Vnn3
0.35
—
0.31
sp∣Q03626
Murinoglobulin-1
0.35
—
0.40
sp∣Q63207
Coagulation factor X
0.36
—
0.37
sp∣D3ZTE0
Coagulation factor XII
0.43
1.84
0.79
tr∣Q68FY4
Group specific component
0.45
2.22
—
sp∣P17475
Alpha-1-antiproteinase
0.46
2.74
1.25
tr∣A9CME3
Complement component 4 binding protein, alpha
0.49
2.20
—
sp∣P01015
Angiotensinogen
0.49
2.72
1.46
tr∣G3V8B1
Glycosylphosphatidylinositol specific phospholipase D1, isoform CRA_a
