Suppressive Effect of the n-Hexane Extract of Litsea japonica Fruit Flesh on Monosodium-Iodoacetate-Induced Osteoarthritis in Rats

Figure 4

Effects of LJF-HE on the mRNA expression levels of cytokines in the joint tissues of rats with MIA-induced OA. (a) Representative histological analysis (H&E staining) of the knee joint in MIA-induced OA. (b–e) The mRNA expression levels of IL-1β, IL-6, COX-2, and TNF-α in the joint tissues of rats with MIA-induced OA were measured by real-time PCR. indicates when compared to saline group (NC). indicates and indicates when compared to the control group (CTL).

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