Research Article

Molecular Targets and Associated Potential Pathways of Danlu Capsules in Hyperplasia of Mammary Glands Based on Systems Pharmacology

Table 2

Information regarding HMG-related targets of DLCs.

NumberTarget ID Target nameGene

TAR00003Nitric-oxide synthase, inducibleNOS2
TAR00006Prostaglandin G/H synthase 1PTGS1
TAR00016Muscarinic acetylcholine receptor M3CHRM3
TAR00046Estrogen receptorESR1
TAR00048Androgen receptorAR
TAR00070Sodium channel protein type 5 subunit alphaSCN5A
TAR00078Peroxisome proliferator activated receptor gammaPPARG
TAR00086Apoptosis regulator Bcl-2BCL2
TAR00094Prostaglandin G/H synthase 2PTGS2
TAR00095Nitric-oxide synthase, endothelialNOS3
TAR00139Vascular endothelial growth factor receptor 2KDR
TAR00153Ornithine decarboxylaseODC1
TAR00154Muscarinic acetylcholine receptor M4CHRM4
TAR00165AcetylcholinesteraseACHE
TAR001755-Hydroxytryptamine 2A receptorHTR2A
TAR00209Progesterone receptorPGR
TAR00210Muscarinic acetylcholine receptor M2CHRM2
TAR0023872 kDa type IV collagenaseMMP2
TAR00246Cytosolic phospholipase A2PLA2G4A
TAR00261Beta-2 adrenergic receptorADRB2
TAR00265Tumor necrosis factorTNF
TAR00288Aldose reductaseAKR1B1
TAR00298Epidermal growth factor receptorEGFR
TAR00299Mu-type opioid receptorOPRM1
TAR00306Multidrug resistance-associated protein 1ABCC1
TAR00307Estrogen receptor betaESR2
TAR00346Urokinase-type plasminogen activatorPLAU
TAR00349Hepatocyte growth factor receptorMET
TAR00351Interleukin-6IL6
TAR00353Interstitial collagenaseMMP1
TAR00363Cathepsin DCTSD
TAR00365Interferon gammaIFNG
TAR00374Fatty acid synthaseFASN
TAR00402Mitogen-activated protein kinase 14MAPK14
TAR00404Transient receptor potential cation channel subfamily V member 1TRPV1
TAR00414Transcription factor AP-1JUN
TAR00417C-C motif chemokine 2CCL2
TAR00418Interleukin-1 betaIL1B
TAR00427E-selectinSELE
TAR00428MyeloperoxidaseMPO
TAR00436Gap junction alpha-1 proteinGJA1
TAR00441Stromelysin-1MMP3
TAR00444Heat shock protein HSP 90Hsp90
TAR00466Tissue factorF3
TAR00470NAD(P)H dehydrogenase [quinone] 1NQO1
TAR00521Leukotriene A-4 hydrolaseLTA4H
TAR00568Xanthine dehydrogenase/oxidaseXDH
TAR00573Cell division protein kinase 4CDK4
TAR00581Neuronal acetylcholine receptor protein, alpha-7 chainCHRNA7
TAR00597Superoxide dismutase [Cu-Zn]SOD1
TAR00621Cytochrome P450 3A4CYP3A4
TAR00646Cellular tumor antigen p53TP53
TAR00647Serine/threonine-protein kinase Chk1CHEK1
TAR00704Mitogen-activated protein kinase 8MAPK8
TAR00724Cytochrome P450 1A2CYP1A2
TAR00733Glutathione S-transferase PGSTP1
TAR00734Proepidermal growth factorEGF
TAR00740Vascular endothelial growth factor AVEGFA
TAR02132Heme oxygenase 1HMOX1
TAR02915Retinoblastoma-associated proteinRB1
TAR02966Protooncogene serine/threonine-protein kinase Pim-1PIM1
TAR03204Aryl hydrocarbon receptorAHR
TAR03276Nuclear receptor coactivator 2NCOA2
TAR03279Nuclear receptor coactivator 1NCOA1
TAR03971Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformPPP3CA
TAR03978Interleukin-2IL2