Icariin Prevents IL-1<i>β</i>-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway

<div>Given 20 <i>μ</i>g/mL of IL-1<i>β</i> for 48 h, human NP cells exhibited a decline in MMP. The group pretreated with icariin exhibited a stable mitochondrial membrane potential. When the PI3K/AKT pathway was blocked, this protective effect was weakened. 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Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Icariin Prevents IL-1<i>β</i>-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway 

Evidence-Based Complementary and Alternative Medicine

Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway

Figure 4