Research Article

Influences of Realgar-Indigo naturalis, A Traditional Chinese Medicine Formula, on the Main CYP450 Activities in Rats Using a Cocktail Method

Table 1

Standard curves, correlation coefficients, linear ranges, and LLOQ of analytes in rat plasma.

NumberStandard curvesLinear range (μg⋅ml−1)LLOQ (μg⋅ml−1)

Caffeine0.9990.21–2150.21
Chlorzoxazone0.9990.41–406.40.11
Tolbutamide0.9990.44–445.20.09
Midazolam0.9990.42–440.10.13