Roles of Nitric Oxide and Prostaglandins in the Sustained Antihypertensive Effects of Acanthospermum hispidum DC. on Ovariectomized Rats with Renovascular Hypertension

Table 3

Effects of oral administration of purified aqueous extract obtained from A. hispidum DC. (ESAH) on urinary volume and electrolyte excretion, pH, and density on 7th day of treatment.

Group	Urinary volume					pH	Density
	(ml/100 g/8 h)	(µEq/min/100 g)	(µEq/min/100 g)	(µEq/min/100 g)	(µEq/min/100 g)
Sham
C+
ESAH (30 mg/kg)
ESAH (100 mg/kg)
ESAH (300 mg/kg)
ENAL
HCTZ

Values are expressed as mean ± SEM of 6-7 rats in each group in comparison with the positive control (C+; ) or Sham-operated group () using one-way ANOVA followed by Dunnett’s test. El: excreted load; HCTZ: hydrochlorothiazide; ENAL: enalapril.