Inhibition of Cardiac Hypertrophy Effects in D-Galactose-Induced Senescent Hearts by Alpinate Oxyphyllae Fructus Treatment

Table 1

Heart weight and echocardiographic indices.

	Control	Induced aging (IA)	IA + AL	IA + AM	IA + AH
Body weight (g)	456 ± 31.05	462 ± 32.32	437 ± 61.02	444 ± 31.4	464 ± 15.6
WHW (g)	1.39 ± 0.06	1.55 ± 0.07	1.39 ± 0.10	1.37 ± 0.03	1.40 ± 0.03
LVW (g)	0.99 ± 0.06	1.11 ± 0.06	0.95 ± 0.11	0.96 ± 0.02	0.97 ± 0.02
WHW/tibia (10^2)	3.10 ± 0.09	3.52 ± 0.2	3.35 ± 0.23	3.25 ± 0.08	3.37 ± 0.10
LVW/tibia (10^2)	2.20 ± 0.09	2.54 ± 0.13	2.28 ± 0.24	2.30 ± 0.05	2.33 ± 0.08
IVSD (mm)	1.37 ± 0.08	1.31 ± 0.12	1.43 ± 0.16	1.31 ± 0.12	1.38 ± 0.10
LVIDd (mm)	9.15 ± 0.62	9.67 ± 0.73	8.89 ± 0.34	9.20 ± 0.12	9.02 ± 0.50
LVPWd (mm)	1.32 ± 0.12	1.50 ± 0.14	1.35 ± 0.08	1.10 ± 0.09	1.23 ± 0.07
LVIDs (mm)	6.09 ± 0.75	6.17 ± 0.83	5.12 ± 0.27	5.99 ± 0.31	5.05 ± 0.25

Values are means ± SD; at least in each group. AL, AOF low; AM, AOF medium; AH, AOF high; WHW, whole heart weight; LVW, left ventricular weight; WHW/tibia, whole heart weight normalized by tibia length; LVW/tibia, left ventricular weight normalized by tibia length; IVSD, interventricular septal thickness at end-diastole; LVIDd, left ventricular internal dimension at end-diastole; LVPWd, left ventricular posterior wall thickness at end-diastole; LVIDs, left ventricular internal dimension at end-systole. and compared to the control group; , , and compared to the induced aging group, respectively.