Figure 1: Effects of hEIF formulation on ovary weight and serum FSH concentrations of the control and test groups after 3 weeks of treatment. Sprague–Dawley rats with a mean body weight of 110 g were given hEIF extract for 3 weeks, and the effects on precocious puberty were identified. The prepared hEIF extract was administered orally at 50, 100, and 200 mg/kg BW to rats. compared with the control value. hEIF: herbal estrogen inhibition formulae. FSH: follicle stimulating hormone.