Clinical Efficacy and Safety of Total Glucosides of Paeony for Primary Sjögren’s Syndrome: A Systematic Review

Table 1

Characteristics of studies.

Study	EG		CG		Interventions		Course	Main outcome
					EG	CG
Feng and Zhang 2008 [20]	42	30	36	20	TGP + MTX	MTX	3 months	A + B + D + E
He 2008 [21]	26	19	22	9	TGP + HCQ	HCQ	3 months	A + B + C + D + E
Cai 2011 [22]	30	25	30	17	TGP + MTX	MTX	6 months	A + B + C + D
Yin 2011 [23]	42	32	39	16	TGP + HCQ	HCQ	3 months	A + B + C + D
Lin et al. 2011 [24]	34	25	32	14	TGP + HCQ	HCQ	24 weeks	A + B + C + D
H. Zhao and F.-T. Zhao 2013 [25]	28	26	26	24	TGP + HCQ	HCQ	6 months	A + C + D
Liu and Deng 2016 [26]	28	24	28	16	TGP + MTX	MTX	6 months	A + B + C + D

Note. EG: experimental group, CG: control group, : total cases, : effective cases, TGP: total glucosides of paeony, HCQ: hydroxychloroquine, MTX: methotrexate, A: effective rate, B: adverse reaction, C: clinical symptoms and signs, D: laboratory indices, E: security indices.