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Evidence-Based Complementary and Alternative Medicine
Volume 2017 (2017), Article ID 3687486, 11 pages
Research Article

Effect of Modified Pulsatilla Powder on Enterotoxigenic Escherichia coli O101-Induced Diarrhea in Mice

Natural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China

Correspondence should be addressed to Zhongqiong Yin

Received 6 March 2017; Revised 26 April 2017; Accepted 26 April 2017; Published 17 July 2017

Academic Editor: Vincenzo De Feo

Copyright © 2017 Jiankang Yu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


MPP can be effective in the treatment of E. coli O101-induced diarrhea in mice. MPP can improve the weight loss caused by diarrhea, increase spleen and thymus indices, and reduce the diarrhea index. MPP can reduce the number of WBC, regulate the level of cytokines, and regulate the intestinal microbial flora. These data suggest that MPP is a promising candidate for treatment of E. coli-induced diarrhea in humans and animals.