Screening of Natural Bioactive Metabolites and Investigation of Antioxidant, Antimicrobial, Antihyperglycemic, Neuropharmacological, and Cytotoxicity Potentials of Litsea polyantha Juss. Ethanolic Root Extract
Table 2
Neuropharmacological effect of ethanol extract of Litsea polyantha on open field test.
Treatment (oral) group
Number of squares crossed by the mice
0 min
30 min
60 min
90 min
120 min
180 min
Negative control
117.2 ± 3.89
89.00 ± 1.95
76.80 ± 1.50
71.0 ± 2.07
79.60 ± 1.88
82.40 ± 1.33
Positive control (diazepam)
125.60 ± 2.56
37.0 ± 1.41
31.0 ± 0.84
28.0 ± 0.89
32.4 ± 0.60
29.8 ± 0.80
Root (250 mg/kg)
119.0 ± 2.81
68.8 ± 2.03
54.6 ± 1.63
50.6 ± 2.5
61.2 ± 2.6
70.20 ± 2.67
Root (500 mg/kg)
120.60 ± 3.8
59.2 ± 0.80
48.8 ± 2.22
44.8 ± 2.22
57.4 ± 3.4
65.2 ± 0.66
and when compared with negative control. The significance level for individual experiment period has been shown in Supplementary Table .
